Drug Detail


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Drug Name Tisotumab vedotin-tftv
Trade Name Tivdak
Synonyms HuMax-TF-ADC|TF-011-MMAE
Drug Descriptions

Tivdak (tisotumab vedotin-tftv) is an antibody-drug conjugate consists of anti-tissue factor (TF) antibody and the cytotoxic agent monomethyl auristatin E (MMAE), which induces killing of tumor cells overexpressing tissue factor (PMID: 24371232, PMID: 31796521). Tivdak (tisotumab vedotin-tftv) is FDA approved fro use in patients with with recurrent or metastatic cervical cancer (FDA.gov).

CAS Registry Number 1418731-10-8
NCIT ID C113164


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Tisotumab vedotin-tftv Bevacizumab Tisotumab vedotin-tftv 0 1
Carboplatin + Tisotumab vedotin-tftv Carboplatin Tisotumab vedotin-tftv 0 1
Pembrolizumab + Tisotumab vedotin-tftv Pembrolizumab Tisotumab vedotin-tftv 0 1
Tisotumab vedotin-tftv Tisotumab vedotin-tftv 0 5

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