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Drug Name LY2603618
Trade Name
Synonyms
Drug Descriptions

LY2603618 is a small molecule that inhibits CHK1, which may lead to disruption of DNA synthesis, early mitosis, and apoptosis, and may increase tumor cell sensitivity to chemotherapeutics (PMID: 24114124).

DrugClasses CHK1 Inhibitor 14

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cisplatin + LY2603618 + Pemetrexed Disodium Cisplatin LY2603618 Pemetrexed Disodium 1 0
Gemcitabine + LY2603618 Gemcitabine LY2603618 1 0
LY2603618 LY2603618 0 0
LY2603618 + Pemetrexed Disodium LY2603618 Pemetrexed Disodium 1 0


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