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Drug Name MIW815
Trade Name
Synonyms ADUS100|ADU-S100|NVP-MIW815
Drug Descriptions

MIW815 (ADUS100) is a synthetic cyclic dinucleotide that acts as an activator for the stimulation of interferon gene signaling (STING1), resulting in T cell differentiation and infiltration of the tumor, thereby possibly resulting in tumor regression (PMID: 28483787, PMID: 31355488).

DrugClasses STING1 Agonist 10
CAS Registry Number 1638241-89-0
NCIT ID C125902


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ipilimumab + MIW815 Ipilimumab MIW815 0 1
MIW815 MIW815 0 1
MIW815 + Pembrolizumab MIW815 Pembrolizumab 0 1
MIW815 + Spartalizumab MIW815 Spartalizumab 2 1

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