Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Drug Name | RO7198457 |
Trade Name | |
Synonyms | RG 6180|RG-6180|RG6180|RO-7198457|RO 7198457 |
Drug Descriptions |
RO7198457 is a personalized neoantigen-specific immunotherapy that stimulates T-cell mediated immune response against tumor cells, potentially resulting in antitumor activity (Cancer Res (2020) 80 (16_Supplement): CT301). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C140162 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin + RO7198457 | Atezolizumab Fluorouracil Irinotecan Leucovorin Oxaliplatin RO7198457 | 0 | 1 |
Atezolizumab + RO7198457 | Atezolizumab RO7198457 | 0 | 2 |
Pembrolizumab + RO7198457 | Pembrolizumab RO7198457 | 0 | 1 |
RO7198457 | RO7198457 | 0 | 2 |