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Drug Name Autogene cevumeran
Trade Name
Synonyms RG 6180|RG-6180|RG6180|RO-7198457|RO 7198457|RO7198457|BNT 122|BNT-122|BNT122
Drug Descriptions

Autogene cevumeran (RO7198457) is a personalized neoantigen-specific immunotherapy that stimulates T-cell mediated immune response against tumor cells, potentially resulting in antitumor activity (PMID: 37165196).

CAS Registry Number 2365453-34-3
NCIT ID C175745


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Autogene cevumeran Atezolizumab Autogene cevumeran 0 2
Atezolizumab + Autogene cevumeran + Fluorouracil + Irinotecan + Leucovorin + Oxaliplatin Atezolizumab Autogene cevumeran Fluorouracil Irinotecan Leucovorin Oxaliplatin 0 2
Autogene cevumeran Autogene cevumeran 0 2
Autogene cevumeran + Pembrolizumab Autogene cevumeran Pembrolizumab 0 1

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