Drug Detail


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Drug Name BGB659
Trade Name
Synonyms ML 786
Drug Descriptions

BGB659 is a pan-RAF inhibitor that results in inhibition of MEK/ERK signaling generated by either RAF dimers or RAF monomers and thus, prevents cell proliferation (PMID: 26343582).

DrugClasses RAF Inhibitor (Pan) 23
CAS Registry Number 1237536-18-3


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Therapy Name Drugs Efficacy Evidence Clinical Trials
BGB659 BGB659 2 0
BGB659 + Cetuximab BGB659 Cetuximab 2 0

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