Drug Detail

Drug Name CHIR-124
Trade Name
Synonyms
Drug Descriptions

CHIR-124 is a selective inhibitor of CHK1, which may enhance sensitivity of tumor cells to chemotherapeutic agents (PMID: 17255282, PMID: 22244109).

DrugClasses CHK1 Inhibitor 14

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Camptothecin + CHIR-124 CHIR-124 Camptothecin 2 0
CHIR-124 CHIR-124 0 0
CHIR-124 + Gemcitabine CHIR-124 Gemcitabine 1 0
CHIR-124 + Irinotecan CHIR-124 Irinotecan 1 0
CHIR-124 + SN-38 CHIR-124 SN-38 2 0


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