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SGN-CD123A is an antibody-drug conjugate comprising a CD123-targeted antibody linked to pyrrolobenzodiazepine dimers, which delivers the DNA cross-linking agent agent to CD123-expressing tumor cells, potentially resulting in increased tumor cell death and decreased tumor growth (PMID: 29142066).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Quizartinib + SGN-CD123A||Quizartinib SGN-CD123A||0||0|