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Drug Name AG-270
Trade Name
Synonyms AG270|AG 270
Drug Descriptions

AG-270 inhibits methionine adenosyltransferase II alpha (MAT2A), to induce cell death of tumor cells reliant on S-Adenosyl-L-methionine (SAM) synthesis (NCI Drug Dictionary).

CAS Registry Number 13299-99-5
NCIT ID C153180


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AG-270 AG-270 0 1
AG-270 + Docetaxel AG-270 Docetaxel 0 1
AG-270 + Gemcitabine + Nab-paclitaxel AG-270 Gemcitabine Nab-paclitaxel 0 1

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