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Drug Name LMB-100
Trade Name
Synonyms RG7787|RO-6927005|RO6927005|LMB100
Drug Descriptions

LMB-100 is an immunotoxin that targets mesothelin, potentially resulting in antitumor activity (PMID: 27863199, PMID: 32611684).

CAS Registry Number 1841500-93-3
NCIT ID C121653


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ipilimumab + LMB-100 Ipilimumab LMB-100 0 1
LMB-100 LMB-100 1 3
LMB-100 + Nab-paclitaxel LMB-100 Nab-paclitaxel 0 2
LMB-100 + Pembrolizumab LMB-100 Pembrolizumab 0 2
LMB-100 + SVP-rapa LMB-100 SVP-rapa 0 1
LMB-100 + Tofacitinib LMB-100 Tofacitinib 0 1

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