Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name Samuraciclib
Trade Name
Synonyms CT 7001|CT7001|CT-7001|ICEC0942
Drug Descriptions

Samuraciclib (ICEC0942) is an orally available and selective CDK7 inhibitor that prevents Cdk7 phosphorylation to induce cell cycle arrest and apoptosis (PMID: 29545334, PMID: 32150405).

DrugClasses CDK7 Inhibitor 16
CAS Registry Number 1805789-54-1
NCIT ID C155652


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Elacestrant + Samuraciclib Elacestrant Samuraciclib 0 1
Fulvestrant + Samuraciclib Fulvestrant Samuraciclib 0 2
Pexidartinib + Samuraciclib Pexidartinib Samuraciclib 0 0
Samuraciclib Samuraciclib 0 1
Samuraciclib + Tamoxifen Samuraciclib Tamoxifen 0 0
Samuraciclib + Vepdegestrant Samuraciclib Vepdegestrant 0 1

Additional content available in CKB BOOST