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Drug Name IDE196
Trade Name
Synonyms LXS196|IDE 196|IDE-196|Darovasertib
Drug Descriptions

IDE196 (LXS196) is an inhibitor of protein kinase C (PKC), thereby blocking signaling pathways triggered by PKC, which may result in cell cycle arrest and apoptosis (AACR Annual Meeting 2019, Abstract CT068).

DrugClasses PKC Inhibitor (Pan) 11
CAS Registry Number 1874276-76-2
NCIT ID C124796


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Binimetinib + IDE196 Binimetinib IDE196 0 0
Crizotinib + IDE196 Crizotinib IDE196 0 1
IDE196 IDE196 0 4
IDE196 + Siremadlin IDE196 Siremadlin 0 1
IDE196 + Trametinib IDE196 Trametinib 0 0

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