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Drug Name AO-108
Trade Name
Synonyms
Drug Descriptions

AO-108 is an antibody against CD47 that binds to and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, leading to phagocytosis of tumor cells and may also stimulate cytotoxic T-cells (PMID: 29873856).

DrugClasses CD47 Antibody 30 Immune Checkpoint Inhibitor 147
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AO-108 AO-108 0 0


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