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Drug Name | AO-108 |
Trade Name | |
Synonyms | |
Drug Descriptions |
AO-108 is an antibody against CD47 that binds to and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, leading to phagocytosis of tumor cells and may also stimulate cytotoxic T-cells (PMID: 29873856). |
DrugClasses | CD47 Antibody 30 Immune Checkpoint Inhibitor 147 |
CAS Registry Number | NA |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AO-108 | AO-108 | 0 | 0 |