Drug Detail


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Drug Name Cadonilimab
Trade Name
Synonyms AK-104|AK 104|AK104
Drug Descriptions

Cadonilimab is a bispecific antibody that targets CD274 (PD-L1) and CTLA-4, potentially resulting in enhanced anti-tumor immune response (PMID: 36872527).

DrugClasses CTLA4 Antibody 28 Immune Checkpoint Inhibitor 146 PD-L1/PD-1 antibody 112
CAS Registry Number 2233593-44-5
NCIT ID C153379


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AK119 + Cadonilimab AK119 Cadonilimab 0 1
AK127 + Cadonilimab AK127 Cadonilimab 0 1
Anlotinib + Cadonilimab Anlotinib Cadonilimab 0 0
Cadonilimab Cadonilimab 0 2
Cadonilimab + Capecitabine + Oxaliplatin Cadonilimab Capecitabine Oxaliplatin 0 0
Cadonilimab + Chiauranib Cadonilimab Chiauranib 0 1
Cadonilimab + Lenvatinib Cadonilimab Lenvatinib 0 0

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