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Drug Name AK104
Trade Name
Synonyms AK-104|AK 104
Drug Descriptions

AK104 is a monoclonal antibody against CD274 (PD-L1) that inhibits binding to the PDCD1 (PD1) receptor, potentially resulting in enhanced anti-tumor immune response (PMID: 29932513).

DrugClasses Immune Checkpoint Inhibitor 153 PD-L1/PD-1 antibody 100
CAS Registry Number 2233593-44-5
NCIT ID C153379


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Therapy Name Drugs Efficacy Evidence Clinical Trials
AK104 AK104 0 2
AK104 + AK119 AK104 AK119 0 1
AK104 + AK127 AK104 AK127 0 1
AK104 + Anlotinib AK104 Anlotinib 1 0
AK104 + Capecitabine + Oxaliplatin AK104 Capecitabine Oxaliplatin 0 0
AK104 + Lenvatinib AK104 Lenvatinib 0 0

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