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| Drug Name | Naxitamab |
| Trade Name | Danyelza |
| Synonyms | hu3F8 |
| Drug Descriptions |
Danyelza (naxitamab) is an antibody that targets the ganglioside GD2, potentially resulting in increased anti-tumor immune response against GD2-expressing tumor cells (PMID: 22754766). Danyelza (naxitamab) is FDA approved for use in combination with GM-CSF in pediatric patients one year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who achieved a partial response, minor response, or stable disease to prior therapy (FDA.gov). |
| DrugClasses | |
| CAS Registry Number | 1879925-92-4 |
| NCIT ID | C123428 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Aldesleukin + Cyclophosphamide + Naxitamab | Aldesleukin Cyclophosphamide Naxitamab | 0 | 1 |
| Ceritinib + Naxitamab | Ceritinib Naxitamab | 0 | 1 |
| Irinotecan + Naxitamab + Sargramostim + Temozolomide | Irinotecan Naxitamab Sargramostim Temozolomide | 0 | 2 |
| Isotretinoin + Naxitamab + Sargramostim | Isotretinoin Naxitamab Sargramostim | 0 | 1 |
| Naxitamab | Naxitamab | 0 | 1 |
| Naxitamab + Sargramostim | Naxitamab Sargramostim | 0 | 3 |
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