Drug Detail


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Drug Name Naxitamab
Trade Name Danyelza
Synonyms hu3F8
Drug Descriptions

Danyelza (naxitamab) is an antibody that targets the ganglioside GD2, potentially resulting in increased anti-tumor immune response against GD2-expressing tumor cells (PMID: 22754766). Danyelza (naxitamab) is FDA approved for use in combination with GM-CSF in pediatric patients one year of age and older and adult patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow who achieved a partial response, minor response, or stable disease to prior therapy (FDA.gov).

CAS Registry Number 1879925-92-4
NCIT ID C123428


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldesleukin + Cyclophosphamide + Naxitamab Aldesleukin Cyclophosphamide Naxitamab 0 1
Ceritinib + Naxitamab Ceritinib Naxitamab 0 1
Gemcitabine + Naxitamab + TGF-beta-imprinted NK cells Gemcitabine Naxitamab TGF-beta-imprinted NK cells 0 1
Irinotecan + Naxitamab + Sargramostim + Temozolomide Irinotecan Naxitamab Sargramostim Temozolomide 0 2
Isotretinoin + Naxitamab + Sargramostim Isotretinoin Naxitamab Sargramostim 0 1
Naxitamab Naxitamab 0 1
Naxitamab + Sargramostim Naxitamab Sargramostim 0 3

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