Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name PF-06952229
Trade Name
Synonyms PF06952229|PF 06952229
Drug Descriptions

PF-06952229 is an inhibitor of the transforming growth factor-beta receptor 1 (TGFBR1), which results in stimulation of the immune system (NCI Drug Dictionary).

DrugClasses TGFBR1 inhibitor 16
CAS Registry Number NA
NCIT ID C160258


  • Case insensitive filtering will display rows where any text in any cell matches the filter term
  • Simple literal full or partial string matches
  • Separate multiple filter terms with a spaces, order doesn't matter (a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page, filtering has no impact on query parameters
  • Use quotes to match a longer phrase which contains spaces "mtor c1483f"


  • Generally, the default sort order for tables is set to be first column ascending, however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column, be sure to set ascending or descending order for a given column, before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Enzalutamide + PF-06952229 Enzalutamide PF-06952229 0 1
Letrozole + Palbociclib + PF-06952229 Letrozole PF-06952229 Palbociclib 0 1
PF-06952229 PF-06952229 0 1

Additional content available in CKB BOOST