Drug Detail


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Drug Name ADCT-601
Trade Name
Synonyms ADCT601|ADCT 601|BGB 601|BGB601|BGB-601
Drug Descriptions

ADCT-601 (BGB 601) is an antibody-drug conjugate (ADC) comprising an antibody targeting AXL linked to PL1601, which delivers the cytotoxic agent SG3199 to AXL-expressing tumor cells, potentially leading to decreased tumor growth (Cancer Res July 1 2018 (78) (13 Supplement) 2792A).

DrugClasses AXL Antibody 5
CAS Registry Number NA
NCIT ID C160890


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ADCT-601 ADCT-601 0 2
ADCT-601 + Gemcitabine ADCT-601 Gemcitabine 0 1
ADCT-601 + Olaparib ADCT-601 Olaparib 0 0

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