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| Drug Name | EGFR806-specific CAR T cells |
| Trade Name | |
| Synonyms | autologous CD4+/CD8+ T cells expressing EGFR806-specific CAR/EGFRt |
| Drug Descriptions |
EGFR806-specific CAR T cells are autologous T-cells engineered with a lentiviral vector to express a chimeric antigen receptor that targets EGFR present in abnormal conformational states, including EGFRvIII and other activating mutants, which result in enhanced anti-tumor response against EGFR-expressing tumors (NCI Drug Dictionary). |
| DrugClasses | EGFR Immune Cell Therapy 3 |
| CAS Registry Number | NA |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| EGFR806-specific CAR T cells | EGFR806-specific CAR T cells | 0 | 1 |
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