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Drug Name Botensilimab
Trade Name
Synonyms AGEN1181|AGEN 1181|AGEN-1181
Drug Descriptions

Botensilimab (AGEN1181) is an antibody that targets CTLA4, potentially resulting in increased anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2021;9).

DrugClasses CTLA4 Antibody 29 Immune Checkpoint Inhibitor 147
CAS Registry Number NA
NCIT ID C158557

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AGEN1571 + Balstilimab + Botensilimab AGEN1571 Balstilimab Botensilimab 0 1
AGEN1571 + Botensilimab AGEN1571 Botensilimab 0 1
AgenT-797 + Balstilimab + Botensilimab + Paclitaxel + Ramucirumab AgenT-797 Balstilimab Botensilimab Paclitaxel Ramucirumab 0 1
Balstilimab + Bevacizumab + Botensilimab + Fluorouracil + Leucovorin + Oxaliplatin Balstilimab Bevacizumab Botensilimab Fluorouracil Leucovorin Oxaliplatin 0 2
Balstilimab + Botensilimab Balstilimab Botensilimab 0 7
Balstilimab + Botensilimab + Celecoxib + Chloroquine phosphate + Cisplatin + Gemcitabine + Nab-paclitaxel Balstilimab Botensilimab Celecoxib Chloroquine phosphate Cisplatin Gemcitabine Nab-paclitaxel 0 1
Balstilimab + Botensilimab + Fluorouracil + Leucovorin + Oxaliplatin + Panitumumab Balstilimab Botensilimab Fluorouracil Leucovorin Oxaliplatin Panitumumab 0 1
Balstilimab + Botensilimab + GS-1423 Balstilimab Botensilimab GS-1423 0 1
Balstilimab + Botensilimab + Regorafenib Balstilimab Botensilimab Regorafenib 0 1
Botensilimab Botensilimab 0 3
Botensilimab + Gemcitabine + Nab-paclitaxel Botensilimab Gemcitabine Nab-paclitaxel 0 1


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