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Drug Name Tesetaxel
Trade Name
Synonyms DJ-927
Drug Descriptions

Tesetaxel (DJ-927) is a taxane that stabilizes tubulin and inhibits microtubule disassembly, potentially resulting in increased cytotoxicity in tumor cells and decreased tumor growth (PMID: 12824894, PMID: 21547572).

DrugClasses Antimicrotubule Agent 14
CAS Registry Number 333754-36-2
NCIT ID C37451

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Tesetaxel Atezolizumab Tesetaxel 0 1
Capecitabine + Tesetaxel Capecitabine Tesetaxel 0 2
Itraconazole + Tesetaxel Itraconazole Tesetaxel 0 0
Nivolumab + Tesetaxel Nivolumab Tesetaxel 0 1
Pembrolizumab + Tesetaxel Pembrolizumab Tesetaxel 0 1
Rifampin + Tesetaxel Rifampin Tesetaxel 0 0
Tesetaxel Tesetaxel 0 1


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