Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
SL-279252 is a chimeric fusion protein that consists of the extracellular domains of PD-1 (PDCD1) and OX40L (TNFSF4) linked by an Fc domain, which may result in both immune checkpoint inhibition and TNF receptor activation, leading to increased antitumor immune response (PMID: 30563566).
|DrugClasses||Immune Checkpoint Inhibitor 146|
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|