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Drug Name ARV-471
Trade Name
Synonyms ARV471|ARV 471
Drug Descriptions

ARV-471 is a bifunctional molecule that targets the estrogen receptor (ESR1), including ESR1 variants, for proteolytic degradation resulting in reduced target gene expression and potentially leading to reduced cell proliferation and inhibition of tumor growth (Cancer Res 2019;79(4 Suppl):Abstract nr P5-04-18, PMID: 32829249).

DrugClasses Hormone - Anti-estrogens 22
CAS Registry Number 2229711-68-4
NCIT ID C165420


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Therapy Name Drugs Efficacy Evidence Clinical Trials
ARV-471 ARV-471 0 1
ARV-471 + Palbociclib ARV-471 Palbociclib 0 1

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