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Drug Name LOAd703
Trade Name
Synonyms Delolimogene mupadenorepvec
Drug Descriptions

LOAd703 (delolimogene mupadenorepvec) is an adenovirus engineered to express trimerized human CD40L and full-length 4-1BBL, resulting in activation of CD40L and 4-1BBL signaling, and potentially leading to reduced tumor cell viability and decreased tumor growth (PMID: 28536305).

CAS Registry Number NA
NCIT ID C148462


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Atezolizumab + Gemcitabine + LOAd703 + Nab-paclitaxel Atezolizumab Gemcitabine LOAd703 Nab-paclitaxel 0 1
Atezolizumab + LOAd703 Atezolizumab LOAd703 0 1
Gemcitabine + LOAd703 Gemcitabine LOAd703 0 0
Gemcitabine + LOAd703 + Nab-paclitaxel Gemcitabine LOAd703 Nab-paclitaxel 0 1
LOAd703 LOAd703 0 0

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