Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name MEDI5752
Trade Name
Synonyms MEDI-5752|MEDI 5752|volrustomig
Drug Descriptions

MEDI5752 is a bispecific human IgG1 monoclonal antibody that binds PD1 (PDCD1) and CTLA4, potentially resulting in enhanced anti-tumor immune response (Cancer Res 2018;78(13 Suppl):Abstract nr 2776).

DrugClasses CTLA4 Antibody 30 Immune Checkpoint Inhibitor 148 PD-L1/PD-1 antibody 117
CAS Registry Number NA
NCIT ID C171937

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Axitinib + MEDI5752 Axitinib MEDI5752 0 1
Bevacizumab + MEDI5752 Bevacizumab MEDI5752 0 1
Capecitabine + Fluorouracil + MEDI5752 + Trastuzumab deruxtecan Capecitabine Fluorouracil MEDI5752 Trastuzumab deruxtecan 0 1
Capecitabine + MEDI5752 + Oxaliplatin Capecitabine MEDI5752 Oxaliplatin 0 1
Carboplatin + Datopotamab deruxtecan + MEDI5752 Carboplatin Datopotamab deruxtecan MEDI5752 0 1
Carboplatin + MEDI5752 + Paclitaxel Carboplatin MEDI5752 Paclitaxel 0 1
Carboplatin + MEDI5752 + Paclitaxel + Pemetrexed Disodium Carboplatin MEDI5752 Paclitaxel Pemetrexed Disodium 0 0
Carboplatin + MEDI5752 + Pemetrexed Disodium Carboplatin MEDI5752 Pemetrexed Disodium 0 3
Carboplatin + MEDI5752 + Trastuzumab deruxtecan Carboplatin MEDI5752 Trastuzumab deruxtecan 0 1
Datopotamab deruxtecan + MEDI5752 Datopotamab deruxtecan MEDI5752 0 1
Fluorouracil + Leucovorin + MEDI5752 + Oxaliplatin Fluorouracil Leucovorin MEDI5752 Oxaliplatin 0 1
Lenvatinib + MEDI5752 Lenvatinib MEDI5752 0 1
MEDI5752 MEDI5752 0 7
MEDI5752 + Monalizumab MEDI5752 Monalizumab 0 1
MEDI5752 + Trastuzumab deruxtecan MEDI5752 Trastuzumab deruxtecan 0 1


Additional content available in CKB BOOST