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Drug Name AOH1160
Trade Name
Synonyms
Drug Descriptions

AOH1160 is a small molecule inhibitor that specifically targets cancer associated PCNA (caPCNA) and binds to the region between L126 and Y133, thereby interfering with elongation of the replication fork, and subsequently leading to cell cycle arrest, apoptosis, and tumor growth inhibition (PMID: 29967249).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AOH1160 AOH1160 1 0
AOH1160 + Cisplatin AOH1160 Cisplatin 0 0


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