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Drug Name AsiDNA
Trade Name
Synonyms
Drug Descriptions

AsiDNA is an oligodeoxyribonucleotide drug that acts as a DNA repair pathway antagonist by mimicking double-stranded DNA breaks and subsequently recruiting DNA repair proteins, thereby preventing the repair of other DNA damaged sites, and thus, potentially leading to increased cell death and inhibition of cell proliferation (PMID: 27559053, PMID: 32839491).

DrugClasses
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AsiDNA AsiDNA 0 2
AsiDNA + AZD2461 AZD2461 AsiDNA 0 0
AsiDNA + Carboplatin AsiDNA Carboplatin 0 1
AsiDNA + Carboplatin + Paclitaxel AsiDNA Carboplatin Paclitaxel 0 1
AsiDNA + Iniparib AsiDNA Iniparib 0 0
AsiDNA + Niraparib AsiDNA Niraparib 0 1
AsiDNA + Olaparib AsiDNA Olaparib 0 1
AsiDNA + Rucaparib AsiDNA Rucaparib 0 0
AsiDNA + Talazoparib AsiDNA Talazoparib 0 0
AsiDNA + Veliparib AsiDNA Veliparib 0 0


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