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Drug Name | AMG 160 |
Trade Name | |
Synonyms | HLE-BiTE AMG 160|AMG-160|AMG160 |
Drug Descriptions |
AMG 160 is a bi-specific T-cell engager (BiTE) antibody that binds to PSMA and CD3, potentially resulting in enhanced T-cell response and antitumor activity against PSMA-expressing tumor cells (PMID: 33504551). |
DrugClasses | PSMA Antibody 12 |
CAS Registry Number | NA |
NCIT ID | C157282 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Abiraterone + AMG 160 | AMG 160 Abiraterone | 0 | 1 |
AMG 160 | AMG 160 | 0 | 2 |
AMG 160 + AMG 404 | AMG 160 AMG 404 | 0 | 1 |
AMG 160 + Enzalutamide | AMG 160 Enzalutamide | 0 | 1 |
AMG 160 + Pembrolizumab | AMG 160 Pembrolizumab | 0 | 1 |
AMG 160 + unspecified PD-1 antibody | AMG 160 unspecified PD-1 antibody | 0 | 0 |