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Drug Name MGD019
Trade Name
Synonyms MGD-019|MGD 019|AEX-1344|AEX1344|lorigerlimab
Drug Descriptions

MGD019 is a tetravalent, dual-affinity re-targeting (DART) protein that potentially inhibits PD-1 (PDCD1) and CTLA4, resulting in enhanced immune response against cancer cells expressing PD-1 and CTLA4 (Keystone Symposia Conference, 2019, Feb. 18-22, Abs nr: 1012).

DrugClasses CTLA4 Inhibitor 4 Immune Checkpoint Inhibitor 146
CAS Registry Number NA
NCIT ID C158505

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Docetaxel + MGD019 + Prednisone Docetaxel MGD019 Prednisone 0 1
MGC018 + MGD019 MGC018 MGD019 0 1
MGD019 MGD019 0 2


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