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| Drug Name | JZP-458 |
| Trade Name | |
| Synonyms | JZP458|JZP 458|RC-P JZP-458|crisantaspase biobetter JZP-458 |
| Drug Descriptions |
JZP-458 is a recombinant asparaginase derived from the Erwinia chrysanthemi bacterium, which converts L-asparagine to L-aspartic acid and ammonia resulting in decreased L-asparagine levels, leading to inhibition of protein synthesis and potentially decreasing tumor cell proliferation (NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C167120 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| JZP-458 | JZP-458 | 0 | 1 |
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