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Drug Name JZP-458
Trade Name
Synonyms JZP458|JZP 458|RC-P JZP-458|crisantaspase biobetter JZP-458
Drug Descriptions

JZP-458 is a recombinant asparaginase derived from the Erwinia chrysanthemi bacterium, which converts L-asparagine to L-aspartic acid and ammonia resulting in decreased L-asparagine levels, leading to inhibition of protein synthesis and potentially decreasing tumor cell proliferation (NCI Drug Dictionary).

DrugClasses
CAS Registry Number NA
NCIT ID C167120

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Therapy Name Drugs Efficacy Evidence Clinical Trials
JZP-458 JZP-458 0 1


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