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|Synonyms||JZP458|JZP 458|RC-P JZP-458|crisantaspase biobetter JZP-458|
JZP-458 is a recombinant asparaginase derived from the Erwinia chrysanthemi bacterium, which converts L-asparagine to L-aspartic acid and ammonia resulting in decreased L-asparagine levels, leading to inhibition of protein synthesis and potentially decreasing tumor cell proliferation (NCI Drug Dictionary).
|CAS Registry Number||NA|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|