Drug Detail


Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Drug Name SAR441000
Trade Name
Synonyms SAR 441000|SAR-441000|BNT 131|BNT131|BNT-131
Drug Descriptions

SAR441000 is a mixture of mRNA encoding IL-12sc, IL-15sushi, IFNa and GM-CSF that when taken up by cells is translated and released into the tumor microenvironment, potentially resulting in immune system activation and antitumor immune response (NCI Drug Dictionary).

CAS Registry Number NA
NCIT ID C166375


  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")


  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Cemiplimab + SAR441000 Cemiplimab SAR441000 0 1
SAR441000 SAR441000 0 1

Additional content available in CKB BOOST