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GSK-LSD1 is an irreversible KDM1A inhibitor that covalently binds to the FAD pocket and blocks enzymatic activity of KDM1A, thereby potentially inhibiting cell viability and tumor growth (PMID: 29997151, PMID: 26175415).
|DrugClasses||KDM1A Inhibitor 12|
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|