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Drug Name Brexucabtagene autoleucel
Trade Name Tecartus
Synonyms KTE-X19|KTEX19|KTE X19
Drug Descriptions

Tecartus (brexucabtagene autoleucel) are autologous T-cells engineered to express an anti-CD-19 chimeric antigen receptor (CAR), which may potentially target CD-19-expressing tumor cells (PMID: 32242358). Tecartus (brexucabtagene autoleucel) is FDA approved for use in adult patients with relapsed or refractory mantle cell lymphoma and patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (FDA.gov).

DrugClasses
CAS Registry Number NA
NCIT ID C170439

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Brexucabtagene autoleucel Brexucabtagene autoleucel 0 1
Brexucabtagene autoleucel + Cyclophosphamide + Fludarabine Brexucabtagene autoleucel Cyclophosphamide Fludarabine 0 3


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