Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Drug Name | LOXO-305 |
Trade Name | |
Synonyms | LOXO 305|LOXO305|pirtobrutinib |
Drug Descriptions |
LOXO-305 selectively inhibits activation of BTK, which results in decreased tumor growth (PMID: 32170458, PMID: 33676628). |
DrugClasses | BTK inhibitor 32 |
CAS Registry Number | NA |
NCIT ID | C158617 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cyclophosphamide + Doxorubicin + LOXO-305 + Prednisone + Rituximab + Vincristine Sulfate | Cyclophosphamide Doxorubicin LOXO-305 Prednisone Rituximab Vincristine Sulfate | 0 | 1 |
LOXO-305 | LOXO-305 | 11 | 6 |
LOXO-305 + LOXO-338 | LOXO-305 LOXO-338 | 0 | 1 |
LOXO-305 + Rituximab + Venetoclax | LOXO-305 Rituximab Venetoclax | 0 | 2 |
LOXO-305 + Venetoclax | LOXO-305 Venetoclax | 0 | 2 |