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Drug Name | Tinengotinib |
Trade Name | |
Synonyms | TT00420|TT 00420|TT-00420 |
Drug Descriptions |
TT-00420 is a multikinase inhibitor that targets AURKA, AURKB, FGFR1-3, VEGFR, JAK1/2, and CSF1R, potentially resulting in decreased cell proliferation and inhibition of tumor growth (PMID: 36223547). |
DrugClasses | Aurka Inhibitors 25 Aurkb Inhibitors 21 CSF1R Inhibitor 28 FGFR1 Inhibitor 27 FGFR2 Inhibitor 22 FGFR3 Inhibitor 19 JAK Inhibitor (Pan) 9 VEGFR Inhibitor (Pan) 35 |
CAS Registry Number | 2230490-29-4 |
NCIT ID | C162532 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Nab-paclitaxel + Tinengotinib | Nab-paclitaxel Tinengotinib | 0 | 1 |
Tinengotinib | Tinengotinib | 0 | 3 |