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Drug Name FT596
Trade Name
Synonyms
Drug Descriptions

FT596 consists of induced pluripotent stem cell (iPSC)-derived natural killer cells engineered to express a CD19 targeting chimeric antigen receptor (CAR), a fusion protein consisting of IL15 and IL-15R alpha, and CD16, which may lead to enhanced cytotoxicity in CD19-expressing tumor cells (Blood (2019) 134 (Supplement_1): 301).

DrugClasses

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + Fludarabine + FT596 Cyclophosphamide FT596 Fludarabine 0 1
Cyclophosphamide + Fludarabine + FT596 + Obinutuzumab Cyclophosphamide FT596 Fludarabine Obinutuzumab 0 1
Cyclophosphamide + Fludarabine + FT596 + Rituximab Cyclophosphamide FT596 Fludarabine Rituximab 0 1
FT596 FT596 0 0
FT596 + Rituximab FT596 Rituximab 0 0


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