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Drug Name | Anti-PSCA(dCH2)BBz-CAR T-cells |
Trade Name | |
Synonyms | anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T lymphocytes |
Drug Descriptions |
Anti-PSCA(dCH2)BBz-CAR T-cells are T-cells that have been engineered to express a PSCA-targeted chimeric antigen receptor (CAR) containing a 4-1BB signaling domain and truncated CD19, which may increase death of PSCA-expressing tumor cells and and decrease tumor growth (PMID: 29308300). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C157746 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Anti-PSCA(dCH2)BBz-CAR T-cells | Anti-PSCA(dCH2)BBz-CAR T-cells | 0 | 2 |