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|Drug Name||Autologous HERV-E TCR transduced T cells|
|Synonyms||Autologous CT-RCC-1 HERV-E-TCR-transduced-HLA-A11-restricted CD8+/CD34t+ T-cells|
Autologous HERV-E TCR transduced T cells are patient-derived T-cells that have been engineered to express a T-cell receptor (TCR) that targets an HLA-A-A11-restricted HERV-E peptide, which potentially results in increased anti-tumor immune response against HERV-E-expressing tumor cells and increased tumor cell killing (Annals of Oncology (2018) 29 (suppl_8): viii303-viii331).
|Therapy Name||Drugs||Efficacy Evidence||Clinical Trials|
|Autologous HERV-E TCR transduced T cells||Autologous HERV-E TCR transduced T cells||0||1|