Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@jax.org
Drug Name | CE7R CAR T cells |
Trade Name | |
Synonyms | CD171 CAR+ T Cells|CD171-specific CAR-CD28 zeta-4-1-BB-EGFRt-expressing T cells |
Drug Descriptions |
CE7R CAR T cells are autologous T-cells that are engineered to express a CD171-targeted chimeric antigen receptor that contains CD28, CD3zeta, and 4-1-BB signaling domains as well as truncated EGFR, which potentially increases cytoxicity in CD171-expressing tumors (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C119746 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CE7R CAR T cells | CE7R CAR T cells | 0 | 1 |