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Drug Name Anti-CD19CAR-CD28-CD3zeta-EGFRt T cells
Trade Name
Drug Descriptions

Anti-CD19CAR-CD28-CD3zeta-EGFRt T cells consist of a defined proportion of CD4 and CD8 positive autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) containing an anti-CD19 fragment linked to the CD28 and CD3zeta signaling domain and a truncated human epidermal growth factor receptor (EGFRt), which has potential cytotoxic activity against CD19-expressing tumor cells (NCI Thesaurus).

CAS Registry Number NA
NCIT ID C137866


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Therapy Name Drugs Efficacy Evidence Clinical Trials
Anti-CD19CAR-CD28-CD3zeta-EGFRt T cells Anti-CD19CAR-CD28-CD3zeta-EGFRt T cells 0 3
Anti-CD19CAR-CD28-CD3zeta-EGFRt T cells + Iomab-B Anti-CD19CAR-CD28-CD3zeta-EGFRt T cells Iomab-B 0 1

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