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Drug Name TP-1454
Trade Name
Synonyms TP1454|TP 1454
Drug Descriptions

TP-1454 is a pyruvate kinase M2 (PKM2) activator, which may inhibit tumor cell viability and tumor growth, and enhance anti-tumor immune response in combination with other agents (Mol Cancer Ther December 1 2019 (18) (12 Supplement) B080).

DrugClasses
CAS Registry Number NA
NCIT ID NA

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Ipilimumab + Nivolumab + TP-1454 Ipilimumab Nivolumab TP-1454 0 1
TP-1454 TP-1454 1 1
TP-1454 + unspecified CTLA4 antibody TP-1454 unspecified CTLA4 antibody 1 0
TP-1454 + unspecified CTLA4 antibody + unspecified PD-1 antibody TP-1454 unspecified CTLA4 antibody unspecified PD-1 antibody 1 0
TP-1454 + unspecified PD-1 antibody TP-1454 unspecified PD-1 antibody 1 0


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