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Gene Symbol CDH2
Synonyms ACOGS | ADHD8 | ARVD14 | CD325 | CDHN | CDw325 | NCAD
Gene Description CDH2, cadherin 2, encodes N-Cadherin, an extracellular matrix protein that plays a significant role in cell migration and invasion, especially during embryonic development (PMID: 15349821). CDH2 has been shown to be either upregulated or overexpressed in a variety of cancer types including, but not limited to melanoma, and, downregulation of CDH2 has been observed in neuroblastoma (PMID: 24442140).
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