Gene Detail


Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at :

Gene Symbol AKT3
Synonyms MPPH | MPPH2 | PKB-GAMMA | PKBG | PRKBG | RAC-gamma | RAC-PK-gamma | STK-2
Gene Description AKT3, AKT serine/threonine kinase 3, is a serine-threonine protein kinase, which regulates cell proliferation and survival through PI3K signaling (PMID: 18955974). AKT3 mutations have been identified in melanoma (PMID: 18813315), altered expression has been observed in breast cancer (PMID: 31320990), and Akt3 is downregulated by several micro-RNAs to inhibit cell migration and invasion (PMID: 31383783, PMID: 31160577, PMID: 31074018, PMID: 30825222).

Additional content available in CKB BOOST