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|Synonyms||MPPH | MPPH2 | PKB-GAMMA | PKBG | PRKBG | RAC-gamma | RAC-PK-gamma | STK-2|
|Gene Description||AKT3, AKT serine/threonine kinase 3, is a serine-threonine protein kinase, which regulates cell proliferation and survival through PI3K signaling (PMID: 18955974). AKT3 mutations have been identified in melanoma (PMID: 18813315), altered expression has been observed in breast cancer (PMID: 31320990), and Akt3 is downregulated by several micro-RNAs to inhibit cell migration and invasion (PMID: 31383783, PMID: 31160577, PMID: 31074018, PMID: 30825222).|