Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol HDAC6
Synonyms CPBHM | HD6 | JM21 | PPP1R90
Gene Description HDAC6, histone deacetylase 6, is a member of the class IIb HDAC family that functions in deacetylation of histone and non-histone proteins to repress transcription (PMID: 30472601) and plays a role in cell migration, angiogenesis, and modification of the immune response (PMID: 30430228, PMID: 30096875). Overexpression of Hdac6 has been observed in oral squamous cell carcinoma, ovarian carcinoma, and primary acute myeloid leukemia (PMID: 30425065).


Additional content available in CKB BOOST