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Gene Symbol CDK8
Synonyms IDDHBA | K35
Gene Description CDK8, cyclin dependent kinase 8, encodes for a member of the mediator complex that binds cyclin-C (CCNC) to regulate gene expression through transcription (PMID: 24043446, PMID: 32071145, PMID: 31248103). Overexpression and/or amplification of CDK8 has been associated with colorectal cancer (PMID: 18794900), gastric cancer, breast cancer, melanoma (PMID: 32206448), and prostate cancer (PMID: 31382571).
Additional content available in CKB BOOST