Gene Detail

Gene Symbol YAP1
Synonyms COB1 | YAP | YAP2 | YAP65 | YKI
Gene Description YAP1, Yes-associated protein 1, is a downstream transcriptional regulator in the Hippo signalling pathway, affecting organ size and tumor formation via cell proliferation and apoptotic control. YAP amplification or over expression has been reported in various cancers (PMID: 17974916, PMID: 22609812).
Entrez Id 10413
Chromosome 11
Map Location 11q22.1
Canonical Transcript NM_001130145

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