Gene Detail

Gene Symbol GPNMB
Synonyms HGFIN | NMB | PLCA3
Gene Description GPNMB, transmembrane glycoprotein NMB, plays a role in osteoblast differentiation, bone mineral deposition, cell invasion, and motility (PMID: 29441921, PMID: 29344282). GPNMB overexpression has been observed in melanoma, breast cancer, glioma, and gastrointestinal cancer (PMID: 29344282).
Entrez Id 10457
Chromosome 7
Map Location 7p15.3
Canonical Transcript NM_001005340


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