Gene Detail


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Gene Symbol CTCF
Synonyms CFAP108 | FAP108 | MRD21
Gene Description CTCF, CCCTC-binding factor (zinc finger protein), is a DNA binding transcriptional repressor of numerous genes including MYC (PMID: 8649389) and TP53 (PMID: 21465478). Ctcf missense variants have been identified in endometrial cancer, prostate cancer, Wilms’ tumor, and breast cancer (PMID: 28648147).

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