Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol CTCF
Synonyms CFAP108 | FAP108 | MRD21
Gene Description CTCF, CCCTC-binding factor (zinc finger protein), is a DNA binding transcriptional repressor of numerous genes including MYC (PMID: 8649389) and TP53 (PMID: 21465478). Ctcf missense variants have been identified in endometrial cancer, prostate cancer, Wilms’ tumor, and breast cancer (PMID: 28648147).


Additional content available in CKB BOOST