Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol POLD3
Synonyms P66 | P68 | PPP1R128
Gene Description POLD3, DNA polymerase delta 3, accessory subunit, is one of four subunits that form the DNA polymerase delta holoenzyme, which mediates DNA replication (PMID: 27320729, PMID: 29447390) and repair (PMID: 31954770), and is required for genome stability (PMID: 27974823). POLD3 amplification and mutations have been identified in colorectal cancer (PMID: 17384679) and breast cancer (PMID: 19706770).


Additional content available in CKB BOOST