Missing content? – Request curation!
Request curation for specific Genes, variants, or PubMed publications.
Have questions, comments or suggestions? - Let us know!
Email us at : email@example.com
|Gene Description||MAP4K1, mitogen-activated protein kinase kinase kinase kinase 1, is a member of the MAPK4 family of serine/threonine kinases that plays a role in negative regulation of T-cell activation and proliferation, and regulates cell signaling pathways involved in cell growth, differentiation, and apoptosis (PMID: 31766293, PMID: 15770651). MAPK41 expression loss has been demonstrated in pancreatic ductal adenocarcinoma (PMID: 19141650).|