Gene Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, variants, or PubMed publications.

Have questions, comments or suggestions? - Let us know!

Email us at : ckbsupport@jax.org

Gene Symbol SUPT16H
Synonyms CDC68 | FACTP140 | SPT16 | SPT16/CDC68
Gene Description SUPT16H, SPT16 homolog facilitates chromatin remodeling subunit, is a component of the FACT (facilitates chromatin transcription) complex, which regulates nucleosome organization (PMID: 21969370) and has histone chaperone activity (PMID: 26841762). Overexpression of Supt16h has been observed in pancreatic ductal adenocarcinoma cell lines (PMID: 25402820).


Additional content available in CKB BOOST