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Gene Symbol SUPT16H
Synonyms CDC68 | FACTP140 | NEDDFAC | SPT16 | SPT16/CDC68
Gene Description SUPT16H, SPT16 homolog facilitates chromatin remodeling subunit, is a component of the FACT (facilitates chromatin transcription) complex, which regulates nucleosome organization (PMID: 21969370) and has histone chaperone activity (PMID: 26841762). Overexpression of Supt16h has been observed in pancreatic ductal adenocarcinoma cell lines (PMID: 25402820).
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