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Gene Symbol U2AF2
Synonyms U2AF65
Gene Description U2AF2, U2 small nuclear RNA auxiliary factor 2, is the large subunit of the U2 auxiliary factor, which recognizes regulatory RNA sequence motifs at the 3' splice site region (PMID: 32303702) and initiates spliceosome assembly (PMID: 1824937, PMID: 27799531). U2AF2 mutations have been identified in a variety of hematologic and solid tumors (PMID: 28850223).

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